SODIUM STARCH GLYCOLATE
SODIUM STARCH GLYCOLATE – Superdisintegrant for Solid Oral Dosage Forms
- Handling: Handle with care to avoid spills; use appropriate protective gloves if necessary.
- Storage: Store in a cool, dry place away from direct sunlight and contamination. Keep containers tightly closed.
- Toxicity: Non-toxic and safe for intended uses.
- Disposal: Dispose of in accordance with local regulations.
Chemical Properties:
- Chemical Name: Carboxymethyl starch sodium salt
- Chemical Formula: (C₆H₁₀O₅)nCOONa
- Appearance: White to off-white, free-flowing powder
- Solubility: Insoluble in most organic solvents; swells extensively in water
- Moisture Content: Typically ≤ 10%
- Particle Size: 90% passing through 100 mesh
Applications:
- Pharmaceutical Industry:
- Used as a superdisintegrant in tablets and hard gelatin capsules
- Suitable for immediate-release formulations
- Compatible with a wide range of APIs and excipients.
Key Benefits:
- Rapid Disintegration: Accelerates tablet breakup in gastrointestinal fluids
- High Swelling Capacity: Ensures fast action at low usage levels (2–8%)
- Non-Toxic & Inert: Safe and compatible with most drug substances
- IP/BP/USP Grades Available: Complies with major pharmacopoeial standards
- Excellent Flow & Compressibility: Suitable for high-speed production
Safety Considerations:
- Handling: Use protective gloves, mask, and goggles; avoid generating dust
- Storage: Store in a dry, cool, well-ventilated area away from moisture
- Toxicity: Non-toxic and safe when used in approved pharmaceutical concentrations
- Disposal: Dispose of in accordance with local environmental regulations